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Hftberger, G

and certain disease states (see Primary systemic carnitine deficiency) (12)

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Patients with IBD are frequently deficient in vitamin K

The subsequent antigen presentation triggers the activation of Th1 and Th17 cells, leading to the release of pro-inflammatory cytokines (IL-2, TNF-, IFN-, IL-17), which in turn amplify oxidative stress and perpetuate an amplifying loop of inflammation and tissue damage (Kubiak et al